From their perch on top of the kidneys, they are responsible for releasing different types of hormones, including cortisol and adrenaline. The adrenal glands, part of the endocrine system, are small. High cortisol also can lead to diabetes, high blood pressure, and weak bones. The adrenal glands pump out unusually high amounts of cortisol, a hormone that ordinarily helps maintain blood pressure and heart and immune function, but when present at high levels for long periods of time can cause weight gain, stretch marks, bruising, acne, and muscle weakness, among other symptoms. Stratakis was beginning his work on adrenal disorders and interpreted Kelly's fluctuating cortisol levels, among other symptoms, as a warning signal of Carney complex, a rare condition that can include benign tumors on multiple organs, including the heart, as well as skin pigmentation and overactive adrenal glands. In 5th grade, after multiple misdiagnoses, she saw an endocrinologist, who then referred her to NIH.ĭr. Kelly had been an avid tap, ballet, and jazz dancer until age 9, when she started suffering from migraines, stomach pain, weight gain, and exhaustion. The discovery he made a decade later helped save Kelly Campbell's life. Constantine Stratakis was a young research fellow at the National Institutes of Health (NIH), he started working on understanding adrenal gland disorders. In the early 1990s, when NICHD Scientific Director Dr.
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